Warts are rough, scaly, spiny
papules or nodules. They can be exist on any cutaneus surface and they are a
manifestation of human papillomavirus (HPV) infection. There is no treatment,which is 100% effective and different types of treatment can be utilised. 16%
Salicylic acid is the best option which is suggested due to evidence based
analysis and for second line treatment cryotherapy is suggested. Bleomycin is
considered as third line therapy, especially encouraged for resistant warts to
conventional methods.
According to the modified evidence based medicine system,
bleomycin has been regarded as level 1 strength of evidence for the treatment
of warts. Bleomycin is derived from ‘Streptomyces verticillus’ and has anantiviral activity by inhibiting DNA synthesis. Since 1970s, numerous reports
have been published on the use of intralesional bleomycin for the treatment of
warts, with cure rates ranging from 14% to 99%.